Concurrent Endometrial Carcinoma in Endometrial Hyperplasia with Atypia
نویسندگان
چکیده
منابع مشابه
Concurrent endometrial carcinoma in patients with a curettage diagnosis of endometrial hyperplasia.
BACKGROUND/PURPOSE Endometrial hyperplasia is considered a precursor of endometrial carcinoma, but concurrent endometrial carcinoma in patients with endometrial hyperplasia is seen frequently. Our aim was to examine the risk factors for coexisting endometrial carcinoma in patients with endometrial hyperplasia. METHODS Between January 1996 and September 2006, 77 patients who underwent hysterec...
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Genes encoding proteins with antioxidant properties may influence susceptibility to endometrial hyperplasia (EH) and endometrial carcinoma (ECa). Patients with EH (n = 89), EH concurrent with ECa (n = 76), ECa (n = 186), and healthy controls (n = 1110) were genotyped for five polymorphic variants in the genes involved in metabolism of lipoproteins (APOE Cys112Arg and Arg158Cys), iron (HFE Cys28...
متن کاملUltrasonographic endometrial thickness measurement is predictive for treatment response in simple endometrial hyperplasia without atypia.
OBJECTIVE We sought to determine the predictors of treatment response in simple endometrial hyperplasia without atypia. MATERIAL AND METHODS We prospectively treated 67 women with simple endometrial hyperplasia without atypia who were administered cyclic oral medroxyprogesterone acetate 10 mg/day for 12 days of luteal phase for 3 months and underwent control endometrial sampling after treatme...
متن کاملP53 Expression in Endometrial Hyperplasia and Endometrial Carcinoma
Background and Objectives: Mutations of the P53 tumor suppressor gene and alterations in its protein expression often occur in a variety of human malignant tumors, including endometrial carcinoma, but the practical implications of this phenomenon are yet to be fully exploited. This study was designed to evaluate P53 protein expression in normal, hyperplastic and malignant endometrium by immunoh...
متن کاملMolecular pathology of endometrial hyperplasia and carcinoma.
Four different genetic abnormalities may occur in endometrioid adenocarcinomas of the endometrium (mircosatellite instability and mutations in the PTEN, k-RAS and beta-catenin genes), whereas nonendometrioid carcinomas of the endometrium often have p53 mutations and loss of heterozygosity on several chromosomes. Occasionally, a nonendometrioid carcinoma may develop as a result of dedifferentiat...
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ژورنال
عنوان ژورنال: Journal of SAFOMS
سال: 2020
ISSN: 2319-846X,2319-9830
DOI: 10.5005/jp-journals-10032-1203